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基石药业-B(02616)CS1001联合化疗用于治疗胃癌的III期临床试验完成首例患者给药

2019-04-16     牛牛财经   来源:
文章摘要:讯,基石药业-B(02616)公告,其自主研发的中国首个全人源及全长抗PD-L1单抗CS1001,联合化疗用于治疗胃腺癌或胃食管结合部腺癌的III期临床试验已完成首例患者给药。该项名为GEMSTONE-303的多中心、安慰剂对照的临床试验,旨在评估CS1001联合XELOX化疗方案(….

xun,基jishiyaoye-B(02616)公gonggao,其qizizhuyanfadezhongguoshougequanrenyuanjiquanchangkangPD-L1单dankangCS1001,联lianhehualiaoyongyuzhiliaoweixianaihuoweishiguanjiehebuxianaideIII期qilinchuangshiyanyiwanchengshoulihuanzhegeiyao。该gaixiangmingweiGEMSTONE-303的deduozhongxin、安anweijiduizhaodelinchuangshiyan,旨zhizaipingguCS1001联lianheXELOX化hualiaofangan(奥aoshalibo+卡kapeitabin)作zuoweiyi线xianzhiliaowufashoushudejubuwanqihuozhuanyixingweixianaihuoweishiguanjiehebuxianaideliaoxiaoheanquanxing

CS1001是shiyoujishiyaoyekaifadezaiyankangPD-L1单dankelongkangti。CS1001由youmeiguogongsiLigand Pharmaceuticals Inc.(LGND.US)授shouquanyinjindeOMT转zhuanjiyindongwupingtaichansheng,该gaipingtaikeshixianquanrenyuankangtideyizhanshishengchan。作zuoweiyizhongquanrenyuanquanchangkangPD-L1单dankelongkangti,CS1001是shiyizhongfanyingrentidetianranG型xingmianyiqiudanbai4(IgG4)单dankangyaowu。与yutongleiyaowuxiangbi,CS1001在zaihuanzhetineichanshengmianyiyuanxingjiqianzaiduxingdefengxiangengdi,这zhe使shideCS1001在zaianquanxingfangmianjuyouqianzaideduteyoushi

CS1001已yizaizhongguowanchengI期qilinchuangyanjiujiliangpapo。在zaiIa期qiyanjiuzhong,CS1001表biaoxianchulianghaodenaishouxinghechixudelinchuanghuoyi。目muqian,有youliangxiangzhucexingII期qilinchuangyanjiuhesanxiangzhucexingIII期qilinchuangyanjiuyijingzaizhongguokaizhan

jishiyaoyedongshichang、执zhixingdongshijianshouxizhixingguanjiangningjunboshibiaoshi,“很hengaoxingkandaoshoulihuanzheruzubinggeiyao,顺shunliqidongIII期qilinchuangshiyan。过guoqujishinian,世shijieshangdaduodiqudeweiaifabinglvhesiwanglvduyousuoxiajiang,但danshizaizhongguo,胃weiaidefabingrenshurengzaishangsheng,胃weixianaiheweishiguanjiehebuxianaimuqianrengyinyiliaoxuqiuyanzhongwufamanzuerchengxianchujudadeyiliaowenti。我womenqiwangCS1001在zaicicizhucelinchuangshiyanzhongqudechenggong,为weizhongguoweiaihuanzhetigongyizhongzhongyaodezhiliaoxinxuanze。”


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